Επιλεγμένες Επιστημονικές Δημοσιεύσεις

@article{,

title = {Comparing hip and knee focused exercises versus hip and knee focused exercises with the use of blood flow restriction training in adults with patellofemoral pain: a randomized controlled trial},

author = {A Constantinou and I Mamais and G Papathanasiou and D Lamnisos and D Stasinopoulos},

doi = {10.23736/s1973-9087.22.06691-6},

issn = {1973-9087},

year  = {2022},

date = {2022-01-01},

urldate = {2022-01-01},

journal = {Eur J Phys Rehabil Med},

abstract = {BACKGROUND: Hip and Knee strengthening exercises are implemented in rehabilitation of patellofemoral pain patients, but typically use high loads (70% of 1 repetition maximum). This may lead to increased patellofemoral joint stress. Low load training (20 - 30% of 1 repetition maximum) with blood flow restriction could allow for exercise strength benefits to proximal and distal muscles with reduced joint stress and by promoting hypoalgesia. AIM: To compare hip and knee focused exercises with and without blood flow restriction in adults with Patellofemoral Pain for short term effectiveness. DESIGN: A randomized observed-blind controlled trial. SETTING: Musculoskeletal laboratories of the European University Cyprus, Nicosia, Cyprus. POPULATION: 60 volunteer patients, 18-40 years of age with Patellofemoral Pain. METHODS: Participants were randomly assigned to (1 reference group) Hip and knee strengthening at (70% of 1 repetition maximum) or (2 experimental group) Strengthening with blood flow restriction at (30% of 1 repetition maximum at 70% of limb occlution pressure). Treatments took place 3 times per week for 4weeks and outcomes were assessed at baseline, end of treatment and at 2months follow up. The primary outcome was the Kujala Anterior Knee Pain Scale and secondary outcomes were worst and usual pain, pain with Single leg Squats, the maximum pain free flexion angle, the Tampa Scale of Kinesiophobia, the Pain Catastrophizing Scale and isometric strength of Knee Extensors, Hip Extensors and Hip Abductors. RESULTS: No difference were found for the main outcome of this study between groups. There was a significant effect of time for all outcome measures in both groups. Between group differences showed a significant difference for isometric strength of Knee extensor values at 2 month follow up F(1,58)=5.56},

note = {1973-9095 

Constantinou, Antonis 

Mamais, Ioannis 

Papathanasiou, Giorgos 

Lamnisos, Demetris 

Stasinopoulos, Dimitrios 

Journal Article 

Italy 

Eur J Phys Rehabil Med. 2022 Jan 5. doi: 10.23736/S1973-9087.22.06691-6.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The Effect of Intensive Close-Kinetic-Chain Exercises on Functionality and Balance Confidence After Total Knee Arthroplasty},

author = {T Tsonga and S Stasi and G Papathanasiou},

doi = {10.7759/cureus.18965},

issn = {2168-8184 (Print) 

2168-8184},

year  = {2021},

date = {2021-01-01},

journal = {Cureus},

volume = {13},

number = {10},

pages = {e18965},

abstract = {Objectives The aim of this study was to evaluate the effects of an additional close-kinetic-chain exercise program (CKC-PT), in conjunction with the standard physiotherapy intervention (TKA-PT), on the general health status, functionality, balance confidence, and postoperative falls of knee osteoarthritic patients who had undergone total knee arthroplasty (TKA). Patients and methods Thirty community-dwellers, aged >65 years, were randomized into equal groups. The Greek versions of the SF-36 version1.0 (SF-36v1.0-Gr), WOMAC(®) (WOMAC(®)-Gr), Activities-specific Balance Confidence scale (ABC-Greek), Timed Up and Go (TUG) test, and Berg Balance Scale were assessed preoperatively and twice postoperatively (7(th) week and 12(th) month). Non-parametric (Mann-Whitney test) and parametric (two-way analysis of variance (ANOVA) model and student t-test) analyses were used to compare the percentage changes in all variables. Results The CKC-PT group reported better (%) functional improvement (WOMAC(®)-Gr Physical- Function subscale) and higher (%) balance confidence (ABS-Greek) at the seventh week and twelfth month as compared to TKA-PT (p<0.05). No other statistically significant differences were observed. Conclusions The implementation of a close-kinetic-chain exercise program, in addition to standard physiotherapy, may significantly increase both the functionality and balance confidence of patients who have undergone TKA. Further studies are needed to verify these findings.},

note = {2168-8184 

Thonga, Theano 

Stasi, Sophia 

Papathanasiou, George 

Journal Article 

Cureus. 2021 Oct 22;13(10):e18965. doi: 10.7759/cureus.18965. eCollection 2021 Oct.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Acute Cardiorespiratory Responses to Different Exercise Modalities in Chronic Heart Failure Patients-A Pilot Study},

author = {E Karatzanos and P Ferentinos and G Mitsiou and S Dimopoulos and A Ntalianis and S Nanas},

doi = {10.3390/jcdd8120164},

issn = {2308-3425},

year  = {2021},

date = {2021-01-01},

journal = {J Cardiovasc Dev Dis},

volume = {8},

number = {12},

abstract = {The purpose of this study was to compare the acute cardiorespiratory responses and time spent above different %VO(2peak) intensities between three "iso-work" protocols: (a) a high intensity interval training protocol (HIIT), (b) a higher intensity continuous protocol (CON(70)) and (c) a lower intensity continuous protocol (CON(50)) in patients with chronic heart failure (CHF). Ten male CHF patients (aged 55.1 ± 16.2 years) performed in separate days a single session of a HIIT protocol consisted of 4 sets × 4 min cycling at 80% VO(2peak) with 3 min of recovery at 50% VO(2peak), a CON(70) protocol corresponding to 70% VO(2peak) and a CON(50) protocol corresponding to 50% VO(2peak). Cardiopulmonary data were collected by an online gas analysis system. The HIIT and CON(70) elicited higher cardiorespiratory responses compared to CON(50) with no differences between them (p > 0.05). In HIIT and CON(70), patients exercised longer at >80% and >90% VO(2peak). The completion rate was 100% for the three protocols. Not any adverse events were observed in either protocol. Both HIIT and CON(70) elicited a stronger physiological stimulus and required shorter time than CON(50). Both HIIT and CON(70) also induced comparable hemodynamic responses and ventilatory demand.},

note = {2308-3425 

Karatzanos, Eleftherios 

Ferentinos, Panagiotis 

Mitsiou, Georgios 

Dimopoulos, Stavros 

Ntalianis, Argyrios 

Nanas, Serafeim 

Journal Article 

J Cardiovasc Dev Dis. 2021 Nov 26;8(12):164. doi: 10.3390/jcdd8120164.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The acute and long-term effects of a cardiac rehabilitation program on endothelial progenitor cells in chronic heart failure patients: Comparing two different exercise training protocols},

author = {C Kourek and M Alshamari and G Mitsiou and K Psarra and D Delis and V Linardatou and T Pittaras and A Ntalianis and C Papadopoulos and N Panagopoulou and I Vasileiadis and S Nanas and E Karatzanos},

doi = {10.1016/j.ijcha.2020.100702},

issn = {2352-9067 (Print) 

2352-9067},

year  = {2021},

date = {2021-01-01},

journal = {Int J Cardiol Heart Vasc},

volume = {32},

pages = {100702},

abstract = {BACKGROUND: Vascular endothelial dysfunction is an underlying pathophysiological feature of chronic heart failure (CHF). Endothelial progenitor cells (EPCs) are also impaired. The purpose of the study was to assess the effect of a cardiac rehabilitation (CR) program on the increase of EPCs at rest and on the acute response after maximal exercise in patients with CHF and investigate whether there were differences between two exercise training protocols and patients of NYHA II and III classes. METHODS: Forty-four patients with stable CHF enrolled in a 36-session CR program and were randomized in one training protocol; either high-intensity interval training (HIIT) or HIIT combined with muscle strength (COM). All patients underwent maximum cardiopulmonary exercise testing (CPET) before and after the CR program and venous blood was drawn before and after each CPET. Five endothelial cellular populations, expressed as cells/10(6) enucleated cells, were quantified by flow cytometry. RESULTS: An increase in all endothelial cellular populations at rest was observed after the CR program (p < 0.01). The acute response after maximum exercise increased in 4 out of 5 endothelial cellular populations after rehabilitation. Although there was increase in EPCs at rest and the acute response after rehabilitation in each exercise training group and each NYHA class, there were no differences between HIIT and COM groups or NYHA II and NYHA III classes (p > 0.05). CONCLUSIONS: A 36-session CR program increases the acute response after maximum CPET and stimulates the long-term mobilization of EPCs at rest in patients with CHF. These benefits seem to be similar between HIIT and COM exercise training protocols and between patients of different functional classes.},

note = {2352-9067 

Kourek, Christos 

Alshamari, Manal 

Mitsiou, Georgios 

Psarra, Katherina 

Delis, Dimitrios 

Linardatou, Vasiliki 

Pittaras, Theodoros 

Ntalianis, Argyrios 

Papadopoulos, Costas 

Panagopoulou, Niki 

Vasileiadis, Ioannis 

Nanas, Serafim 

Karatzanos, Eleftherios 

Journal Article 

Int J Cardiol Heart Vasc. 2020 Dec 24;32:100702. doi: 10.1016/j.ijcha.2020.100702. eCollection 2021 Feb.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Direct anterior approach vs Hardinge in obese and nonobese osteoarthritic patients: A randomized controlled trial},

author = {G Macheras and S Stasi and M Sarantis and A Triantafyllou and D Tzefronis and S A Papadakis},

doi = {10.5312/wjo.v12.i11.877},

issn = {2218-5836 (Print) 

2218-5836},

year  = {2021},

date = {2021-01-01},

journal = {World J Orthop},

volume = {12},

number = {11},

pages = {877-890},

abstract = {BACKGROUND: The increased prevalence of obesity has resulted in orthopedic surgeons being likely to face many patients with a high body mass index (BMI) who warrant total hip arthroplasties (THAs) over the coming years. Studies' findings considered the postoperative clinical, and functional outcomes in these patients are controversial, and selecting the most appropriate surgical approach remains debatable. AIM: To compare pain-levels, functionality, and quality-of-life in obese and nonobese osteoarthritic patients who have undergone primary total hip arthroplasty through either direct-anterior-approach (DAA) or Hardinge-approach. METHODS: One hundred and twenty participants (> 50 years) were divided into four groups according to the surgical approach (DAA or Hardinge) and patients' BMI (nonobese < 30 kg/m(2) vs obese ≥ 30 kg/m(2)). Outcomes were measured preoperatively and postoperatively (6(th) and 12(th) week). Pain was measured with Face Pain Scale-Revised (FPS-R). Functionality was measured with Timed Up & Go (TUG) test and Modified Harris Hip Score-Greek version (MHHS-Gr). Quality-of-life was evaluated with the 12-item-International Hip Outcome Tool-Greek version (iHOT12-Gr) (Clinical Trial Identifier: ISRCTN15066737). RESULTS: DAA vs Hardinge: (week 6) DAA-patients showed 12.2% less pain, more functionality (14.8% shorter TUG-performance time, 21.5% higher MHHS-Gr), and 38.16% better quality-of-life (iHOT12-Gr) compared to Hardinge-patients (all P values < 0.001). These differences were further increased on week 12 (all P values ≤ 0.05)]. DAA-obese vs Hardinge-obese: (week 6) DAA-obese patients had less pain, shorter TUG-performance time, better MHHS-Gr and iHOT12-Gr scores than Hardinge-obese (all P values < 0.01). (Week 12) Only the TUG-performance time of DAA-obese was significantly shortened (22.57%, P < 0.001). DAA-nonobese vs DAA-obese: no statistically significant differences were observed comparing the 6(th) and 12(th) weeks' outcomes. CONCLUSION: DAA-groups reported less pain, more functionality and better quality-of-life, compared to the Hardinge-groups. The DAA benefited obese and nonobese patients, similarly yet faster, suggesting that it should be the more preferred choice for obese patients, instead of Hardinge. However, more comparative studies with more extended follow-up periods are needed to confirm our results and better evaluate all patients' long-term outcomes.},

note = {2218-5836 

Macheras, George 

Stasi, Sophia 

Sarantis, Michail 

Triantafyllou, Athanasios 

Tzefronis, Dimitrios 

Papadakis, Stamatios A 

Clinical Trial 

World J Orthop. 2021 Nov 18;12(11):877-890. doi: 10.5312/wjo.v12.i11.877. eCollection 2021 Nov 18.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Lymphedema duration as a predictive factor of efficacy of complete decongestive therapy},

author = {E Michopoulos and G Papathanasiou and K Krousaniotaki and I Vathiotis and T Troupis and E Dimakakos},

issn = {0024-7766},

year  = {2021},

date = {2021-01-01},

journal = {Lymphology},

volume = {54},

number = {3},

pages = {140-153},

abstract = {Lymphedema is a common condition with global impact and a multitude of complications, however, only a few professionals specialize in its management. A retrospective analysis of 105 subjects with unilateral lymphedema upper or lower limb was performed to investigate whether the duration of lymphedema constitutes an important factor associated with the efficacy of complete decongestive therapy (CDT). Subjects were classified into two groups according to the duration of lymphedema, prior to CDT: group A (≤1 year) and group B (>1 year). Both groups were treated daily according to the same CDT protocol for four weeks. The CDT efficacy was determined based on the percent reduction of excess volume (PREV) measurements. Lymphedema was significantly reduced in both groups of subjects, but significantly more in group A (p<0.001). In subjects with upper limb lymphedema, median value of PREV was 80.8% (interquartile range, 79.1-105.0%) in group A and 62.0% (interquartile range, 56.7-66.5%) in group B (p<0.001). In subjects with lower limb lymphedema PREV was 80.7% (interquartile range, 74.9-85.2%) and 64.5% (interquartile range, 56.0-68.1%) for groups A and B, respectively (p<0.001). Duration of lymphedema was found to be a strong predictive factor that may significantly impact CDT efficacy. Therapeutic effects were increased in subjects who were detected and treated earlier for lymphedema.},

note = {2522-7963 

Michopoulos, E 

Papathanasiou, G 

Krousaniotaki, K 

Vathiotis, I 

Troupis, T 

Dimakakos, E 

Journal Article 

United States 

Lymphology. 2021;54(3):140-153.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Greek population’s perceptions of nonpharmacological interventions towards the first wave of COVID-19 pandemic mitigation: A regressionbased association analysis},

author = {E C Boutsikari and A Christakou and M Elpidoforou and I Kopsidas and N Nikolovienis and D Kardara and C C Boutsikari and C Triantafyllou},

url = {https://doi.org/10.18332/pne/141592},

doi = {10.18332/pne/141592},

issn = {1105-848X},

year  = {2021},

date = {2021-01-01},

journal = {Pneumon},

volume = {34},

number = {3},

pages = {1-11},

abstract = {Introduction In the ongoing coronavirus disease 2019 (COVID-19) pandemic, even though vaccines have been rolled out and the vaccination campaigns in some countries have already been followed by a decline in number and severity of cases, non-pharmaceutical interventions (NPI) are still playing an important role on COVID-19 management (e.g. social distancing) that are imposed by the authorities and require the public’s adherence and behavioral adjustment. This study aims to identify factors that affect the general public’s attitudes towards the importance of NPI in Greece. Methods This prevalence study, enrolled 657 adults from the general Greek population in order to assess their beliefs and identify possible factors that influence their perceptions of NPI. All associations were assessed through multivariate logistic regression. Results Overall, Greeks considered NPI important for health protection. The participants who were less likely to consider NPI important were men compared to women (OR=1.64; 95% CI: 1.15–2.36},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Neurophysiological and ultrasonographic comparative study of autonomous nervous system in patients suffering from fibromyalgia and generalized anxiety disorder},

author = {M Papadopoulou and A Papapostolou and E Bakola and V G Masdrakis and C Moschovos and E Chroni and G Tsivgoulis and I Michopoulos},

doi = {10.1007/s10072-021-05606-3},

issn = {1590-1874},

year  = {2021},

date = {2021-01-01},

journal = {Neurol Sci},

abstract = {BACKGROUND: Fibromyalgia (FM) and generalized anxiety disorder (GAD) share common clinical features: they both affect women more than men, their diagnosis is based solely on clinical criteria, and some of the symptoms such as anxiety, aches and muscle tension, sleep disorders, and cognitive dysfunction occur in both diseases. For both conditions, an underlying dysregulation of the autonomic nervous system (ANS) has been proposed. OBJECTIVE: The aims of this study were to investigate ANS dysfunction in FM and GAD and compare them with controls. METHODS: Sympathetic skin response (SSR) from palm and sole and cross-sectional area (CSA) of bilateral vagus nerves (VN) were measured in 28 healthy controls, 21 FM patients, and 24 GAD patients. RESULTS: CSA of VN was significantly smaller in FM patients (right: 1.97 ± 0.74mm(2), left: 1.75 ± 0.65 mm2) and GAD patients (right: 2.12 ± 0.97mm(2), left: 1.71 ± 0.86 mm(2)) compared to controls (right: 3.21 ± 0.75 mm(2), left: 2.65 ± 1.13 mm(2), p < 0.001, but did not differ between the two patient groups. SSR parameters were similar between patients and controls. SSR latency correlated to clinical scales (FM Widespread Pain Index) in the FM group (r = 0.515, p = 0.02 and r = 0.447, p = 0.05) for the upper and lower limbs respectively, but no other correlation between clinical and neurophysiological parameters was identified. CONCLUSION: This study confirms similar ANS abnormalities in FM and GAD that fairly distinguish them from controls and support the hypothesis of a common pathophysiological substrate underlying both conditions.},

note = {1590-3478 

Papadopoulou, Marianna 

Papapostolou, Apostolos 

Bakola, Eleni 

Masdrakis, Vasilios G 

Moschovos, Christos 

Chroni, Elisabeth 

Tsivgoulis, Georgios 

Michopoulos, Ioannis 

Journal Article 

Italy 

Neurol Sci. 2021 Sep 24. doi: 10.1007/s10072-021-05606-3.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Biomechanical assessment of wear in ceramic on ceramic and ceramic on XLPE THAs},

author = {A Triantafyllou and G Papagiannis and S Stasi and G Papathanasiou and P Koulouvaris and P J Papagelopoulos and G C Babis},

url = {https://doi.org/10.1142/S0219519421500238},

doi = {10.1142/S0219519421500238},

issn = {0219-5194},

year  = {2021},

date = {2021-01-01},

journal = {Journal of Mechanics in Medicine and Biology},

volume = {21},

number = {02},

pages = {2150023},

abstract = {Total Hip Arthroplasty (THA) is an effective treatment for severe hip arthritis, with patients reporting high rates of satisfactory results postoperatively. There are a variety of choices regarding THA implant designs. Ceramic on Ceramic and Ceramic on Highly Cross-Linked Polyethylene (XLPE) THAs are the materials of choice nowadays. The purpose of this study is to review the effect of kinematics and kinetics on wear (in vivo and in vitro testing) that affect wear in Ceramic on Ceramic and Ceramic on XLPE total hip arthroplasties and identify possible advantages amongst them. The study hypothesis was that THA kinematics and/or kinetics, since they directly affect THA wear, could provide data for possible advantages between the examined implant designs. A systematic review of the literature identified no significant evidence for biomechanical advantages between these two prostheses in terms of wear. Further research is proposed with the use of gait analysis systems combined with surface electromyography to further investigate THA biomechanics at a laboratory set up. Wearable sensors technology could also identify detailed biomechanical parameters in more complex daily activities.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Healing potential of the anterior cruciate ligament in terms of fiber continuity after a complete rupture: A systematic review},

author = {A Pitsillides and D Stasinopoulos and K Giannakou},

doi = {10.1016/j.jbmt.2021.06.003},

issn = {1360-8592},

year  = {2021},

date = {2021-01-01},

journal = {J Bodyw Mov Ther},

volume = {28},

pages = {246-254},

abstract = {INTRODUCTION: Complete rupture of the anterior cruciate ligament is a major problem owing to inadequate surgery outcomes and the limited healing capacity of the ligament. This study aimed to summarise the evidence on the spontaneous healing potential of the anterior cruciate ligament in terms of fiber continuity based on magnetic resonance imaging (MRI) findings. METHODS: PubMed, Cochrane Library, Scopus, and MEDLINE databases were searched from their inception to November 1, 2020. Studies that analysed patients diagnosed with complete anterior cruciate ligament rupture were included. Further, studies that used conservative treatment as intervention and MRI finding as an outcome measure were included. RESULTS: In total, 9 studies, with a total of 734 participants, met the inclusion criteria. Knee laxity was measured in all studies. Two studies classified patients according to rupture location, where most ligaments with restored fiber continuity had proximal ruptures. All included studies reported spontaneous healing. Furthermore, none of the included studies reported the absence of healing. CONCLUSIONS: This systematic review demonstrates the intrinsic healing capacity of the anterior cruciate ligament, indicating a higher healing potential for proximal ruptures. While our study reveals an emerging need to question general practice, a definitive conclusion could not be drawn owing to the low quality of the studies included and the heterogeneity of results.},

note = {1532-9283 

Pitsillides, Alexios 

Stasinopoulos, Dimitrios 

Giannakou, Konstantinos 

Journal Article 

Review 

United States 

J Bodyw Mov Ther. 2021 Oct;28:246-254. doi: 10.1016/j.jbmt.2021.06.003. Epub 2021 Jun 12.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Effectiveness and Safety of Complete Decongestive Therapy of Phase I: A Lymphedema Treatment Study in the Greek Population},

author = {E Michopoulos and G Papathanasiou and G Vasilopoulos and M Polikandrioti and E Dimakakos},

doi = {10.7759/cureus.9264},

issn = {2168-8184 (Print) 

2168-8184},

year  = {2020},

date = {2020-01-01},

journal = {Cureus},

volume = {12},

number = {7},

pages = {e9264},

abstract = {Background Lymphedema is a chronic condition caused by a failure in the lymphatic system that most commonly occurs in the limbs. Complete decongestive therapy (CDT) is the gold standard for lymphedema management. Objective To evaluate the effectiveness and safety of complete decongestive therapy (CDT) of phase I in the Greek population with lymphedema. Methods The patients' demographic and clinical characteristics were recorded. CDT was implemented in all patients for 20 sessions in a four-week treatment period. The edema's (excess volume (EV) and percent of excess volume (PEV)) measurements were carried out four times in the treatment period, whereas the percent reduction of excess volume (PREV) was calculated at the end of phase I. Moreover, we recorded every infection, trauma of skin, and pain of limb during the treatment. Results One-hundred five patients with lymphedema were enrolled in the present study, of whom 31.4% had upper limb lymphedema and 68.6% had lower limb lymphedema. All patients with upper limb lymphedema had a secondary type while the corresponding proportion of patients with lower limb lymphedema was 58.3%. A significant reduction (p<0.001) between the pre-treatment and post-treatment values of EV and PEV was found for both upper and lower limb lymphedema. For patients with upper limb lymphedema, the average PREV was 66.5% (interquartile range, 57.3%-80.6%), whereas for patients with lower limb lymphedema, a 71.5% (interquartile range, 64.5%-80.7%) median value was measured. No side effects from the treatment were recorded during CDT. Conclusion The proper treatment of the CDT phase I ensures safety and a great reduction in edema in patients with lymphedema that predispose the success of phase II of CDT.},

note = {2168-8184 

Michopoulos, Emmanouil 

Papathanasiou, George 

Vasilopoulos, Georgios 

Polikandrioti, Maria 

Dimakakos, Evangelos 

Journal Article 

Cureus. 2020 Jul 19;12(7):e9264. doi: 10.7759/cureus.9264.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {International Hip Outcome Tool (12-items) as health-related quality-of-life measure in osteoarthritis: validation of Greek version},

author = {S Stasi and M Stamou and G Papathanasiou and P Frantzeskaki and E Kanavas and G Evaggelou-Sossidis and A Gouskos and A Palantzas and K Poursanidis and G A Macheras},

doi = {10.1186/s41687-020-00207-8},

issn = {2509-8020},

year  = {2020},

date = {2020-01-01},

journal = {J Patient Rep Outcomes},

volume = {4},

number = {1},

pages = {41},

abstract = {BACKGROUND: The 12-item International Hip Outcome Tool (iHOT12) is a patient-reported outcome (PRO) designed to evaluate quality of life. We assessed the psychometric properties of the Greek version (iHOT12-Gr) in hip osteoarthritic patients. METHODS: Data from 124 patients aged > 50 years were used for factor analysis. Reliability evaluation included internal consistency, test-retest reliability, and interpretability. Content validity was examined by calculating the item-level content validity indices (I-CVI) and the scale-level content validity indices (S-CVI), using two methods: S-CVI Average (S-CVI/Ave), and the S-CVI Universal Agreement among experts (S-CVI/UA). Construct validity was tested against Greek versions of the Lower Extremity Functional Scale (LEFS-Greek), Modified Harris Hip Score (MHHS-Gr), and the 30 s chair-to-stand, Timed Up & Go (TUG), and 9-stairs-ascend/descend (9S-A/D) tests. Known-groups validity was examined using LEFS-Greek (cut-off = 53 points) as estimate variable. Responsiveness was examined pre and post total hip arthroplasty (4 and 8 weeks). RESULTS: Factor analysis revealed a two-factor model. Factor-1 (items 1-9) reflects "Symptoms and functionality", while Factor-2 (items 10-12) reflects "Hip disorder-related concerns". Reliability: Internal consistency and test-retest reliability of iHOT12-Gr-total were excellent: Cronbach's alpha > 0.92 and ICC(95% CI) > 0.976(0.96-0.99)(p < 0.001). Interpretability: There was no floor or ceiling effect; measurement error: 3.72 (Factor-1), 3.64 (Factor-2), and 3.22 (iHOT12-Gr-total); minimal detectable change: 10.3 (Factor-1), 10.1 (Factor-2), and 8.92 (iHOT12-Gr-total). VALIDITY: Content validity: The I-CVI value of the 12 items ranged from 1.00 to 0.83, the S-CVI/Ave was 0.97 and the S-CVI/UA was 0.83. Construct validity: iHOT12-Gr correlated strongly with both LEFS-Greek and MHHS-Gr, and weakly but significantly with 30s chair-to-stand, TUG and 9S-A/D (p < 0.001). Known-groups validity showed that iHOT12-Gr well discriminated subgroups of patients (p < 0.001). ROC analysis cut-off points were 51.9 (Factor-1), 25 (Factor-2) and 45.2 (iHOT12-Gr-total) (p < 0.001). Responsiveness: Four and 8 weeks postoperatively, standardized response means of Factor-1, Factor-2, and iHOT12-Gr-total were > 0.8. CONCLUSION: iHOT12-Gr showed excellent reliability properties. The content validity was excellent and significant weak-to-strong correlations were found regarding construct validity. The known-group validity was also significant, while the responsiveness was excellent. iHOT12-Gr could be a reliable and valid PRO for assessing quality of life in patients with hip osteoarthritis.},

note = {2509-8020 

Stasi, Sophia 

Stamou, Magdalini 

Papathanasiou, George 

Frantzeskaki, Paraskevi 

Kanavas, Emmanouil 

Evaggelou-Sossidis, George 

Gouskos, Adamantios 

Palantzas, Andreas 

Poursanidis, Kyriakos 

Macheras, George A 

Journal Article 

J Patient Rep Outcomes. 2020 May 27;4(1):41. doi: 10.1186/s41687-020-00207-8.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Psychometric Properties of the 12-Item World Health Organization Disability Assessment Schedule (WHODAS 2.0) in Adult Patients with Motor Disabilities},

author = {M Papadopoulou and S Stasi and D Bakalidou and E Papageorgiou and A Tsokani and T Bratsi and G Papathanasiou},

url = {https://doi.org/10.1007/s10882-019-09721-0},

doi = {10.1007/s10882-019-09721-0},

issn = {1573-3580},

year  = {2020},

date = {2020-01-01},

journal = {Journal of Developmental and Physical Disabilities},

volume = {32},

number = {5},

pages = {801-819},

abstract = {To explore the psychometric properties of the Greek version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0–12 item) in adult patients suffering from motor disabilities. The questionnaire of WHODAS 2.0–12 item was officially translated and cross-culturally adapted into Greek (WHODAS 2.0–12Gr).136 adult patients with motor disabilities included in the present observational study. A reliability study was carried out to explore WHODAS 2.0–12Gr’s internal consistency (Cronbach’s a), repeatability (Pearson’s r) and test retest test-retest reliability between the WHODAS 2.0–12Gr outcomes of day-1 and day-8 [intra-class correlation coefficients with 95% confidence intervals (ICC 95%CI)], and the convergent validity (item-total correlation) of the questionnaire. Exploratory factor analysis (EFA) was used to explore the construct validity of the WHODAS 2.0–12Gr, while the concurrent validity of the questionnaire was testing against the Greek Medical Outcomes Study 36-item Short Form Health Survey version 1.0 (SF-36v1.0-Gr). Reliability properties: WHODAS 2.0–12Gr Cronbach’s a was 0.814 (p < 0.001), Pearson’s r value was 0.980 (p < 0.001) and ICC (95%CI) was 0.990 (0.985–0.993) (p < 0.001). Validity properties: Pearson’s r values of item-total correlation were ranged from 0.376 to 0.736. EFA extracted a 3-factor model. Regarding concurrent validity, the significant correlations between the WHODAS 2.0–12Gr and the SF36v1.0-Gr ranged from −0.169 to −0.720. WHODAS 2.0–12Gr showed significant high to excellent reliability and significant weak to strong validity properties. Overall, it can be suggested that WHODAS 2.0–12Gr could be a reliable and valid tool for assessing patients with motor disabilities.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Carpometacarpal Dislocation of the Third to Fifth Fingers and an Associated Fracture of the Hamate in a Military Paratrooper},

author = {G Kalinterakis and E Antonogiannakis and A Abdi and G Demetriades and A Koulouktsis and A Syllaios and A Koutras and S Vrouva and A Papagiavis and M Ziogas},

doi = {10.1155/2020/2861604},

issn = {2090-6749 (Print) 

2090-6757},

year  = {2020},

date = {2020-01-01},

journal = {Case Rep Orthop},

volume = {2020},

pages = {2861604},

abstract = {Multiple carpometacarpal dislocations with a simultaneous fracture of the hamate represent less than 1% of all injuries to the hand and wrist regions, with a scarcity of published cases. These injuries usually require a great force, and diagnosis can be missed or delayed because of the high likelihood of other severe concomitant injuries. We report a case of acute closed dislocation of the third through fifth carpometacarpal joints and an associated fracture of the hamate in a military paratrooper. The injury was caused by a wrong landing technique during parachuting. The patient was managed with primary surgical repair, and after a six-month follow-up, he has excellent functional results. The fact that both this clinical entity and the mechanism of injury are very unusual a high index of suspicion is needed, especially for orthopedic surgeons working in military hospitals. Additionally, given that there is a paucity of published cases and optional treatment is controversial, this study corroborates the superiority of surgical repair in a long-term basis.},

note = {2090-6757 

Kalinterakis, Georgios 

Antonogiannakis, Emmanouil 

Abdi, Arezoo 

Demetriades, Georgios 

Koulouktsis, Alexandros 

Syllaios, Athanasios},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The Effect of Intensive Abductor Strengthening on Postoperative Muscle Efficiency and Functional Ability of Hip-Fractured Patients: A Randomized Controlled Trial},

author = {S Stasi and G Papathanasiou and E Chronopoulos and I A Dontas and I P Baltopoulos and N A Papaioannou},

doi = {10.4103/ortho.IJOrtho_183_18},

issn = {0019-5413 (Print) 

0019-5413},

year  = {2019},

date = {2019-01-01},

journal = {Indian J Orthop},

volume = {53},

number = {3},

pages = {407-419},

abstract = {BACKGROUND: Hip fractures are common in the elderly and many patients fail to regain prefracture hip abductor strength or functional status. The purpose of this clinical trial was to compare the effects of an intensive abductor muscle exercise program versus a standard physiotherapy intervention in hip-fractured patients. MATERIALS AND METHODS: Ninety six femoral neck-fractured patients were randomized into equal-sized groups. A 12-week standard physiotherapy program was implemented in the control group(S-PT) whereas an intensive exercise program, emphasizing on abductors' strengthening, was implemented in the research group(I-PT). Abductors' isometric strength of the fractured hip, abductor ratio% in the fractured compared to contralateral hip, and functional level were assessed at the 3(rd) (postintervention) and 6(th) (followup) months. RESULTS: Postintervention, abductors' isometric strength was 35.7% greater (P < 0.0005) and abductor ratio% was 2.5% higher (P < 0.0005) in I-PT group, compared to S-PT group. With regard to functional assessments, I-PT group was 29.1% faster during Timed Up and Go (TUG) test and achieved a 26.7% higher Lower Extremity Functional Scale Greek version's (LEFS-Greek) total score, compared to S-PT group (P < 0.0005). At followup, abductors' isometric strength was 37.0% greater (P < 0.0005) and abductor ratio% was 7.1% higher (P < 0.0005) in I-PT group, compared to S-PT group. In addition, I-PT group was 45.9% faster during TUG test (P < 0.0005) and achieved an 11.2% higher LEFS-Greek total score, compared to S-PT group (P = 0.013). CONCLUSIONS: Compared to the standard physiotherapy intervention, the intensive abductor-strengthening program significantly increased both abductors' isometric strength of the fractured hip and abductor ratio% and resulted in patients' enhanced functional level. CLINICAL TRIAL IDENTIFIER: ISRCTN30713542.},

note = {1998-3727 

Stasi, Sophia 

Papathanasiou, George 

Chronopoulos, Efstathios 

Dontas, Ismene A 

Baltopoulos, Ioannis P 

Papaioannou, Nikolaos A 

Journal Article 

Indian J Orthop. 2019 May-Jun;53(3):407-419. doi: 10.4103/ortho.IJOrtho_183_18.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Comparative Study of Pain Relief in Two Non-Pharmacological Treatments in Patients with Partial Rotator Cuff Tears: A Randomized Trial},

author = {S Vrouva and C Batistaki and E Paraskevaidou and K Chanopoulos and D Kostopoulos and E Stamoulis and G Kostopanagiotou},

doi = {10.5812/aapm.88327},

issn = {2228-7523 (Print) 

2228-7523},

year  = {2019},

date = {2019-01-01},

journal = {Anesth Pain Med},

volume = {9},

number = {2},

pages = {e88327},

abstract = {BACKGROUND: Pain induction is the primary characteristic of a rotator cuff tear while muscle weakness appears as a secondary feature, leading to further disability. OBJECTIVES: The study aimed to determine the effectiveness of physiotherapeutic interventions through transcutaneous electrical nerve stimulation (TENS) or microcurrent electrical nerve stimulation (MENS) in conjunction with kinesiotherapy in patients with partial thickness rotator cuff tear. METHODS: This was a blinded randomized prospective study. The study recruited 42 outpatients with partial rotator cuff tear under conservative treatment selected from the 401 General Military Hospital of Athens and the University General Hospital 'Attikon' during 2015 - 2017. Patients were assessed for pain and disability using the SPADI (shoulder pain and disability index), a numerical rating scale (NRS) for pain, and the EuroQoL-5 questionnaire for the evaluation of the quality of life. The first group received TENS and kinesiotherapy while the second group received MENS and kinesiotherapy. Three measurements were recorded. The first assessment was performed during the initial patient visit; the second after completion of the physiotherapeutic sessions, and the third one three months after the initial assessment. A follow-up ultrasound scan was performed three months after the completion of the therapeutic sessions to assess the anatomical healing of the rotator cuff tear. RESULTS: Repeated measurements analysis indicated a significant improvement in pain scores, functionality, and patients' quality of life (P value < 0.001). Comparison of the two treatment methods did not reveal any significant differences (P value > 0.05) despite the fact that the MENS was associated with a greater improvement in pain intensity and TENS with a greater improvement in functionality and quality of life. CONCLUSIONS: Using MENS and TENS appears to be equally effective in terms of pain relief, functional improvement, and quality of life enhancement in patients.},

note = {2228-7531 

Vrouva, Sotiria 

Batistaki, Chrysanthi 

Paraskevaidou, Efterpi 

Chanopoulos, Konstantinos 

Kostopoulos, Dimitrios 

Stamoulis, Efthimios 

Kostopanagiotou, Georgia 

Journal Article 

Anesth Pain Med. 2019 Apr 10;9(2):e88327. doi: 10.5812/aapm.88327. eCollection 2019 Apr.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}